Anti-inflammatory thalidomide improves islet grafts survival and functions in a xenogenic environment.

Thalidomide possesses both anti-inflammatory and anti-angiogenic properties. This study investigates its potential application in islet transplantation with a xenogenic transplantation model. Transplantation was performed using C57Bl/6 mice and NMRI nu/nu mice as recipients of porcine islets. Moreov...

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Bibliographic Details
Main Authors: Chunguang Chen, Carina Kuehn, Reinhard G Bretzel, Thomas Linn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2708353?pdf=render