Age and Sex Influence the Neuro-inflammatory Response to a Peripheral Acute LPS Challenge

Age and Sex Influence the Neuro-inflammatory Response to a Peripheral Acute LPS Challenge

Aging is associated with an exaggerated response to peripheral inflammatory challenges together with behavioral and cognitive deficits. Studies considering both age and sex remain limited, despite sex dimorphism of astrocytes and microglial cells is largely recognized. To fill this knowledge gap, we...

Full description

Bibliographic Details
Main Authors: Valentina Murtaj, Sara Belloli, Giuseppe Di Grigoli, Maria Pannese, Elisa Ballarini, Virginia Rodriguez-Menendez, Paola Marmiroli, Andrea Cappelli, Valeria Masiello, Cristina Monterisi, Giuseppe Bellelli, Paola Panina-Bordignon, Rosa Maria Moresco
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
aging
neuroinflammation
microglia
astrocytes
18 kDa translocator protein
triggering receptor expressed on myeloid cells 2
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00299/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2019.00299/full

Similar Items