CD200 and Chronic Lymphocytic Leukemia: Biological and Clinical Relevance

CD200, a transmembrane type Ia glycoprotein belonging to the immunoglobulin protein superfamily, is broadly expressed on a wide variety of cell types, such as B lymphocytes, a subset of T lymphocytes, dendritic cells, endothelial and neuronal cells. It delivers immunosuppressive signals through its...

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Bibliographic Details
Main Authors: Giovanni D’Arena, Vincenzo De Feo, Giuseppe Pietrantuono, Elisa Seneca, Giovanna Mansueto, Oreste Villani, Francesco La Rocca, Fiorella D’Auria, Teodora Statuto, Luciana Valvano, Francesca Arruga, Silvia Deaglio, Dimitar G. Efremov, Alessandro Sgambato, Luca Laurenti
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.584427/full