pH/Reduction Dual-Stimuli-Responsive Cross-Linked Micelles Based on Multi-Functional Amphiphilic Star Copolymer: Synthesis and Controlled Anti-Cancer Drug Release

pH/Reduction Dual-Stimuli-Responsive Cross-Linked Micelles Based on Multi-Functional Amphiphilic Star Copolymer: Synthesis and Controlled Anti-Cancer Drug Release

Novel approach has been constructed for preparing the amphiphilic star copolymer pH/reduction stimuli-responsive cross-linked micelles (SCMs) as a smart drug delivery system for the well-controlled anti-tumor drug doxorubicin (DOX) release. The SCMs had a low CMC value of 5.3 mg/L. The blank and DOX...

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Bibliographic Details
Main Authors: Yunwei Huang, Jingye Yan, Shiyuan Peng, Zilun Tang, Cuiying Tan, Jiabao Ling, Wenjing Lin, Xiaofeng Lin, Xihong Zu, Guobin Yi
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Polymers
Subjects:
dual-responsive
cross-linked micelles
drug delivery
release kinetics
release thermodynamics
Online Access:https://www.mdpi.com/2073-4360/12/1/82

Internet

https://www.mdpi.com/2073-4360/12/1/82

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