Chiral Alkyl Halides: Underexplored Motifs in Medicine

Chiral Alkyl Halides: Underexplored Motifs in Medicine

While alkyl halides are valuable intermediates in synthetic organic chemistry, their use as bioactive motifs in drug discovery and medicinal chemistry is rare in comparison. This is likely attributable to the common misconception that these compounds are merely non-specific alkylators in biological...

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Bibliographic Details
Main Authors: Bálint Gál, Cyril Bucher, Noah Z. Burns
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Marine Drugs
Subjects:
alkyl halide
stereochemistry
lipophilicity
anesthetic
clindamycin
corticosteroid
pimecrolimus
sucralose
halomon
lapachone
astins
forazoline
Online Access:http://www.mdpi.com/1660-3397/14/11/206

Internet

http://www.mdpi.com/1660-3397/14/11/206

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