Protein Expression Profiling of Giant Cell Tumors of Bone Treated with Denosumab.

Protein Expression Profiling of Giant Cell Tumors of Bone Treated with Denosumab.

Giant cell tumors of bone (GCTB) are locally aggressive osteolytic bone tumors. Recently, some clinical trials have shown that denosumab is a novel and effective therapeutic option for aggressive and recurrent GCTB. This study was performed to investigate the molecular mechanism underlying the thera...

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Bibliographic Details
Main Authors: Kenta Mukaihara, Yoshiyuki Suehara, Shinji Kohsaka, Keisuke Akaike, Yu Tanabe, Daisuke Kubota, Midori Ishii, Tsutomu Fujimura, Saiko Kazuno, Taketo Okubo, Tatsuya Takagi, Takashi Yao, Kazuo Kaneko, Tsuyoshi Saito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4749282?pdf=render

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http://europepmc.org/articles/PMC4749282?pdf=render

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