Early events in xenograft development from the human embryonic stem cell line HS181--resemblance with an initial multiple epiblast formation.

Xenografting is widely used for assessing in vivo pluripotency of human stem cell populations. Here, we report on early to late events in the development of mature experimental teratoma from a well-characterized human embryonic stem cell (HESC) line, HS181. The results show an embryonic process, inc...

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Bibliographic Details
Main Authors: Karin Gertow, Jessica Cedervall, Seema Jamil, Rouknuddin Ali, Marta P Imreh, Miklos Gulyas, Bengt Sandstedt, Lars Ahrlund-Richter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3227586?pdf=render