Mutations in fibroblast growth factor (FGF8) and FGF10 identified in patients with conotruncal defects

Abstract Background Conotruncal defects (CTDs) are a type of heterogeneous congenital heart diseases (CHDs), but little is known about their etiology. Increasing evidence has demonstrated that fibroblast growth factor (FGF) 8 and FGF10 may be involved in the pathogenesis of CTDs. Methods The variant...

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Bibliographic Details
Main Authors: Kun Sun, Shuang Zhou, Qingjie Wang, Zhuo Meng, Jiayu Peng, Yue Zhou, Wenting Song, Jian Wang, Sun Chen
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Translational Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12967-020-02445-2