Tumor burden talks in cancer treatment with PEGylated liposomal drugs.

PURPOSE: PEGylated liposomes are important drug carriers that can passively target tumor by enhanced permeability and retention (EPR) effect in neoplasm lesions. This study demonstrated that tumor burden determines the tumor uptake, and also the tumor response, in cancer treatment with PEGylated lip...

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Bibliographic Details
Main Authors: Yi-Yu Lin, Hao-Wen Kao, Jia-Je Li, Jeng-Jong Hwang, Yun-Long Tseng, Wuu-Jyh Lin, Ming-Hsien Lin, Gann Ting, Hsin-Ell Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3651236?pdf=render