Role of BMI1 in epithelial ovarian cancer: investigated via the CRISPR/Cas9 system and RNA sequencing

Role of BMI1 in epithelial ovarian cancer: investigated via the CRISPR/Cas9 system and RNA sequencing

Abstract Background B-cell-specific Moloney murine leukemia virus integration site 1 (BMI1) might be an appropriate biomarker in the management of epithelial ovarian cancer (EOC). However, the biological role of BMI1 and its relevant molecular mechanism needs further elaboration. Clustered regularly...

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Bibliographic Details
Main Authors: Qianying Zhao, Qiuhong Qian, Dongyan Cao, Jiaxin Yang, Ting Gui, Keng Shen
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Journal of Ovarian Research
Subjects:
B-cell-specific Moloney murine leukemia virus integration site 1 (BMI1)
Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9
Epithelial ovarian cancer (EOC)
Focal adhesion pathway
PI3K/AKT pathway
Online Access:http://link.springer.com/article/10.1186/s13048-018-0406-z

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http://link.springer.com/article/10.1186/s13048-018-0406-z

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