Celecoxib-induced cytotoxic effect is potentiated by inhibition of autophagy in human urothelial carcinoma cells.

Celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, can elicit anti-tumor effects in various malignancies. Here, we sought to clarify the role of autophagy in celecoxib-induced cytotoxicity in human urothelial carcinoma (UC) cells. The results shows celecoxib induced cellular stress response such as en...

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Bibliographic Details
Main Authors: Kuo-How Huang, Kuan-Lin Kuo, I-Lin Ho, Hong-Chiang Chang, Yuan-Ting Chuang, Wei-Chou Lin, Ping-Yi Lee, Shih-Chen Chang, Chih-Kang Chiang, Yeong-Shiau Pu, Chien-Tso Chou, Chen-Hsun Hsu, Shing-Hwa Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3857231?pdf=render