Scaffold-mediated gating of Cdc42 signalling flux

Scaffold-mediated gating of Cdc42 signalling flux

Scaffold proteins modulate signalling pathway activity spatially and temporally. In budding yeast, the scaffold Bem1 contributes to polarity axis establishment by regulating the GTPase Cdc42. Although different models have been proposed for Bem1 function, there is little direct evidence for an under...

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Bibliographic Details
Main Authors: Péter Rapali, Romain Mitteau, Craig Braun, Aurèlie Massoni-Laporte, Caner Ünlü, Laure Bataille, Floriane Saint Arramon, Steven P Gygi, Derek McCusker
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-03-01
Series:eLife
Subjects:
cell polarity
Rho GTPase
signaling
Online Access:https://elifesciences.org/articles/25257

Internet

https://elifesciences.org/articles/25257

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