Oxymatrine improves intestinal epithelial barrier function involving NF-κB-mediated signaling pathway in CCl4-induced cirrhotic rats.

Accumulating evidence suggests that intestinal epithelial barrier dysfunction plays an important role in the pathogenesis of hepatic cirrhosis and its complications such as gastrointestinal injury and hepatic encephalopathy. To date, there is no cure for cirrhosis-associated intestinal mucosal lesio...

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Main Authors: Jian-Bo Wen, Fang-Qing Zhu, Wei-Guo Chen, Li-Ping Jiang, Jie Chen, Zhao-Peng Hu, Yong-Jian Huang, Zhi-Wei Zhou, Gui-Liang Wang, Hao Lin, Shu-Feng Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4149463?pdf=render