Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation

Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation

Abstract Background Pharmacologic inhibition of bromodomain and extra-terminal (BET) proteins is currently being explored as a new therapeutic approach in cancer. Some studies have also implicated BET proteins as regulators of cell identity and differentiation through their interactions with lineage...

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Bibliographic Details
Main Authors: Archit Trivedi, Aanchal Mehrotra, Caitlin E. Baum, Brandon Lewis, Tupa Basuroy, Thomas Blomquist, Robert Trumbly, Fabian V. Filipp, Vijayasaradhi Setaluri, Ivana L. de la Serna
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Epigenetics & Chromatin
Subjects:
Bromodomain and extra-terminal domain
BET
JQ1
BRD4
MITF
ChIP-Seq
Online Access:http://link.springer.com/article/10.1186/s13072-020-00333-z

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http://link.springer.com/article/10.1186/s13072-020-00333-z

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