Efficient and selective N-alkylation of amines with alcohols catalysed by manganese pincer complexes

Hydrogen borrowing is an attractive method for C-N bond formation - avoiding multiple alkylation products and reducing waste - but often is carried out with noble metals. Here the authors show that a manganese catalyst allows the selective N-alkylation of amines with alcohols.

Bibliographic Details
Main Authors: Saravanakumar Elangovan, Jacob Neumann, Jean-Baptiste Sortais, Kathrin Junge, Christophe Darcel, Matthias Beller
Format: Article
Language:English
Published: Nature Publishing Group 2016-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12641