Glibenclamide in aneurysmatic subarachnoid hemorrhage (GASH): study protocol for a randomized controlled trial

Glibenclamide in aneurysmatic subarachnoid hemorrhage (GASH): study protocol for a randomized controlled trial

Abstract Background Recent findings on the benefits of glibenclamide as a neuroprotective drug have started a new era for prospective studies on sulfonylureas. The effect of glibenclamide blocking the Sur1-Trpm4 channel was examined in models of subarachnoid hemorrhage and stroke, with findings of s...

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Bibliographic Details
Main Authors: Bruno Braga Sisnando da Costa, Isabela Costola Windlin, Edwin Koterba, Vitor Nagai Yamaki, Nícollas Nunes Rabelo, Davi Jorge Fontoura Solla, Manoel Jacobsen Teixeira, Eberval Gadelha Figueiredo
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Trials
Subjects:
Subarachnoid hemorrhage
Brain aneurysms
Glibenclamide
Online Access:http://link.springer.com/article/10.1186/s13063-019-3517-y

Internet

http://link.springer.com/article/10.1186/s13063-019-3517-y

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