Intratumoral heterogeneity for inactivating frameshift mutation of CUX1 and SIRT1 genes in gastric and colorectal cancers

Intratumoral heterogeneity for inactivating frameshift mutation of CUX1 and SIRT1 genes in gastric and colorectal cancers

Both CUX1 and SIRT1 are considered tumor suppressor genes (TSGs), but it is not known whether CUX1 and SIRT1 alterations are different between high microsatellite instability (MSI-H) and microsatellite stable MSI (MSS) cancers. We identified frameshift mutations of CUX1 in 4 cases of color...

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Bibliographic Details
Main Authors: Yun Sol Jo, Min Sung Kim, Nam Jin Yoo, Sug Hyung Lee
Format: Article
Language:English
Published: Termedia Publishing House 2017-11-01
Series:Polish Journal of Pathology
Subjects:
<I>CUX1</I>
<I>SIRT1</I>
tumor suppressor
mutation
intratumoral heterogeneity
Online Access:https://www.termedia.pl/Intratumoral-heterogeneity-for-inactivating-frameshift-mutation-of-CUX1-and-SIRT1-genes-in-gastric-and-colorectal-cancers,55,31025,1,1.html

Internet

https://www.termedia.pl/Intratumoral-heterogeneity-for-inactivating-frameshift-mutation-of-CUX1-and-SIRT1-genes-in-gastric-and-colorectal-cancers,55,31025,1,1.html

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