Docosahexaenoic Acid Enhances Oxaliplatin-Induced Autophagic Cell Death via the ER Stress/Sesn2 Pathway in Colorectal Cancer

Docosahexaenoic Acid Enhances Oxaliplatin-Induced Autophagic Cell Death via the ER Stress/Sesn2 Pathway in Colorectal Cancer

Oxaliplatin is an anticancer drug administered to colorectal cancer (CRC) patients in combination with 5-fluorouracil and antibodies (bevacizumab and cetuximab), thereby significantly improving the survival rate of CRC. However, due to various side effects associated with the above treatment strateg...

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Bibliographic Details
Main Authors: Soyeon Jeong, Dae Yeong Kim, Sang Hee Kang, Hye Kyeong Yun, Jung Lim Kim, Bo Ram Kim, Seong Hye Park, Yoo Jin Na, Min Jee Jo, Yoon A. Jeong, Bu Gyeom Kim, Dae-Hee Lee, Sang Cheul Oh
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
Oxaliplatin
docosahexaenoic acid
Sestrin 2
autophagic cell death
colon cancer
Online Access:https://www.mdpi.com/2072-6694/11/7/982

Internet

https://www.mdpi.com/2072-6694/11/7/982

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