Chitosan nanoparticle-based neuronal membrane sealing and neuroprotection following acrolein-induced cell injury

<p>Abstract</p> <p>Background</p> <p>The highly reactive aldehyde acrolein is a very potent endogenous toxin with a long half-life. Acrolein is produced within cells after insult, and is a central player in slow and progressive "secondary injury" cascades. Ind...

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Bibliographic Details
Main Authors: Shi Riyi, Cho Youngnam, Ben Borgens Richard
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Journal of Biological Engineering
Online Access:http://www.jbioleng.org/content/4/1/2