A low-cost method to test cytotoxic effects of Crotalus vegrandis (Serpentes: Viperidae) venom on kidney cell cultures Un método de bajo costo para probar los efectos citotóxicos del veneno de Crotalus vegrandis (Serpentes: Viperidae) en cultivos de células renales

The pathogenesis of the renal lesion upon envenomation by snakebite has been related to myolysis, hemolysis, hypotension and/or direct venom nephrotoxicity caused by the venom. Both primary and continuous cell culture systems provide an in vitro alternative for quantitative evaluation of the toxicit...

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Bibliographic Details
Main Authors: María E. Girón, Irma Aguilar, Lisandro Romero, Elda E. Sánchez, John c. Pérez, Alexis Rodriguez-Acosta
Format: Article
Language:English
Published: Universidade de São Paulo 2005-06-01
Series:Revista do Instituto de Medicina Tropical de São Paulo
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652005000300006