DNA conformational dynamics: approach to the physical mapping of genome

DNA conformational dynamics: approach to the physical mapping of genome

Recently we have developed a new method for studying DNA based on ultrasound - induced cleavage of DNA sugar-phosphate backbone. Relative cleavage rates of the phosphodiester bonds in all 16 dinucleotides have been determined. The increased amount of data sampling (of more than 20 000 nucleotides) m...

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Bibliographic Details
Main Authors: Yurii Dmitrievich Nechipurenko, Dmitrii Yurievich Nechipurenko, Irina Alekseevna Il’icheva, Mikhail Viktorovich Golovkin, Larisa Andreevna Panchenko, Robert Valentinovich Polozov, Sergey L'vovich Grokhovsky
Format: Article
Language:Russian
Published: Institute of Computer Science 2010-12-01
Series:Компьютерные исследования и моделирование
Subjects:
ultrasonic cleavage of DNA
sequence effects on DNA structure
DNA flexibility
d(CpG) dinucleotide
Online Access:http://crm.ics.org.ru/uploads/crmissues/crm2010-2-4/crm100410.pdf

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http://crm.ics.org.ru/uploads/crmissues/crm2010-2-4/crm100410.pdf

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