Matrix degradability controls multicellularity of 3D cell migration
The fabrication of vascularized 3D tissues requires an understanding of how material properties govern endothelial cell invasion into the surrounding matrix. Here the authors integrate a non-swelling synthetic hydrogel with a microfluidic device to study chemokine gradient-driven angiogenic sproutin...
Main Authors: | Britta Trappmann, Brendon M. Baker, William J. Polacheck, Colin K. Choi, Jason A. Burdick, Christopher S. Chen |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-08-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-00418-6 |
Similar Items
-
A 3D Bioprinter Specifically Designed for the High-Throughput Production of Matrix-Embedded Multicellular Spheroids
by: Robert H. Utama, et al.
Published: (2020-10-01) -
Cell Adhesion and Migration in the Development of Multicellular Organisms
Published: (2019) -
Synthetic extracellular matrices with tailored adhesiveness and degradability support lumen formation during angiogenic sprouting
by: Jifeng Liu, et al.
Published: (2021-06-01) -
Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration
by: William Y. Wang, et al.
Published: (2018-12-01) -
Actomyosin contractility-dependent matrix stretch and recoil induces rapid cell migration
by: William Y. Wang, et al.
Published: (2019-03-01)