Synchrony in Parkinson’s disease: Importance of intrinsic properties of the external globus pallidus

Synchrony in Parkinson’s disease: Importance of intrinsic properties of the external globus pallidus

The mechanisms for the emergence and transmission of synchronized oscillations in Parkinson’s disease, which are potentially causal to motor deficits, remain debated. Aside from the motor cortex and the subthalamic nucleus, the external globus pallidus (GPe) has been shown to be essential for the ma...

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Bibliographic Details
Main Authors: Bettina C. Schwab, Tjitske eHeida, Yan eZhao, Enrico eMarani, Stephan A. van Gils, Richard J A Van Wezel
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Systems Neuroscience
Subjects:
Desynchronization
plasticity
SK channels
HCN channels
Dopamine depletion
Globus Pallidus Externus
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2013.00060/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnsys.2013.00060/full

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