In Vivo GFP Knockdown by Cationic Nanogel-siRNA Polyplexes

In Vivo GFP Knockdown by Cationic Nanogel-siRNA Polyplexes

RNA interference (RNAi) is a powerful tool to treat diseases and elucidate target gene function. Prior to clinical implementation, however, challenges including the safe, efficient and targeted delivery of siRNA must be addressed. Here, we report cationic nanogel nanostructured polymers (NSPs) prepa...

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Bibliographic Details
Main Authors: Arun R. Shrivats, Yuji Mishina, Saadyah Averick, Krzysztof Matyjaszewski, Jeffrey O. Hollinger
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Bioengineering
Subjects:
gene therapy
gene expression
RNA Interference
siRNA
GFP
ATRP
nanostructured polymer
Online Access:http://www.mdpi.com/2306-5354/2/3/160

Internet

http://www.mdpi.com/2306-5354/2/3/160

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