A systematic evaluation of single-cell RNA-sequencing imputation methods

A systematic evaluation of single-cell RNA-sequencing imputation methods

Abstract Background The rapid development of single-cell RNA-sequencing (scRNA-seq) technologies has led to the emergence of many methods for removing systematic technical noises, including imputation methods, which aim to address the increased sparsity observed in single-cell data. Although many im...

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Bibliographic Details
Main Authors: Wenpin Hou, Zhicheng Ji, Hongkai Ji, Stephanie C. Hicks
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Genome Biology
Subjects:
Gene expression
Single-cell RNA-sequencing
Imputation
Benchmark
Online Access:http://link.springer.com/article/10.1186/s13059-020-02132-x

Internet

http://link.springer.com/article/10.1186/s13059-020-02132-x

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