In vivo exposure to codeine induces reproductive toxicity: role of HER2 and p53/Bcl-2 signaling pathway

Several studies have implicated codeine use in the aetiopathogenesis of male infertility. The purpose of this study was to investigate the role of HER2, Ki67, oestrogen and p53/Bcl-2 signaling pathways and the possible outcome of codeine cessation on codeine-induced reproductive toxicity. Thirty adu...

Full description

Bibliographic Details
Main Authors: A.F. Ajayi, R.E. Akhigbe
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Heliyon
Subjects:
p53
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020324324