Neuroprotective Effect of Curcumin on the Nigrostriatal Pathway in a 6-Hydroxydopmine-Induced Rat Model of Parkinson’s Disease is Mediated by α7-Nicotinic Receptors

Neuroprotective Effect of Curcumin on the Nigrostriatal Pathway in a 6-Hydroxydopmine-Induced Rat Model of Parkinson’s Disease is Mediated by α7-Nicotinic Receptors

Parkinson’s disease (PD) is a common neurodegenerative disorder, characterized by selective degeneration of dopaminergic nigrostriatal neurons. Most of the existing pharmacological approaches in PD consider replenishing striatal dopamine. It has been reported that activation of the cholinergic syste...

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Bibliographic Details
Main Authors: Eslam El Nebrisi, Hayate Javed, Shreesh K Ojha, Murat Oz, Safa Shehab
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
Parkinson’s disease
6-OHDA
α7-nAChR
curcumin
neuroprotection
Online Access:https://www.mdpi.com/1422-0067/21/19/7329

Internet

https://www.mdpi.com/1422-0067/21/19/7329

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