An update on the role of intestinal cytochrome P450 enzymes in drug disposition
Oral administration is the most commonly used route for drug treatment. Intestinal cytochrome P450 (CYP)-mediated metabolism can eliminate a large proportion of some orally administered drugs before they reach systemic circulation, while leaving the passage of other drugs unimpeded. A better underst...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-09-01
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Series: | Acta Pharmaceutica Sinica B |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221138351630154X |