c-Abl Tyrosine Kinase Is Regulated Downstream of the Cytoskeletal Protein Synemin in Head and Neck Squamous Cell Carcinoma Radioresistance and DNA Repair

c-Abl Tyrosine Kinase Is Regulated Downstream of the Cytoskeletal Protein Synemin in Head and Neck Squamous Cell Carcinoma Radioresistance and DNA Repair

The intermediate filament synemin has been previously identified as novel regulator of cancer cell therapy resistance and DNA double strand break (DSB) repair. c-Abl tyrosine kinase is involved in both of these processes. Using PamGene technology, we performed a broad-spectrum kinase activity profil...

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Bibliographic Details
Main Authors: Sara Sofia Deville, Luis Fernando Delgadillo Silva, Anne Vehlow, Nils Cordes
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
ionizing radiation
HNSCC
synemin
c-Abl
DNA repair
zebrafish
Online Access:https://www.mdpi.com/1422-0067/21/19/7277

Internet

https://www.mdpi.com/1422-0067/21/19/7277

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