Loss of genetic redundancy in reductive genome evolution.

Biological systems evolved to be functionally robust in uncertain environments, but also highly adaptable. Such robustness is partly achieved by genetic redundancy, where the failure of a specific component through mutation or environmental challenge can be compensated by duplicate components capabl...

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Bibliographic Details
Main Authors: André G Mendonça, Renato J Alves, José B Pereira-Leal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3040653?pdf=render