Inhibition of the Lysophosphatidylinositol Transporter ABCC1 Reduces Prostate Cancer Cell Growth and Sensitizes to Chemotherapy

Inhibition of the Lysophosphatidylinositol Transporter ABCC1 Reduces Prostate Cancer Cell Growth and Sensitizes to Chemotherapy

Expression of ATP-binding cassette (ABC) transporters has long been implicated in cancer chemotherapy resistance. Increased expression of the ABCC subfamily transporters has been reported in prostate cancer, especially in androgen-resistant cases. ABCC transporters are known to efflux drugs but, rec...

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Bibliographic Details
Main Authors: Aikaterini Emmanouilidi, Ilaria Casari, Begum Gokcen Akkaya, Tania Maffucci, Luc Furic, Federica Guffanti, Massimo Broggini, Xi Chen, Yulia Y. Maxuitenko, Adam B. Keeton, Gary A. Piazza, Kenneth J. Linton, Marco Falasca
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
prostate cancer
ABC transporter
ABCC1/MRP1
lysophosphatidylinositol
Docetaxel
Online Access:https://www.mdpi.com/2072-6694/12/8/2022

Internet

https://www.mdpi.com/2072-6694/12/8/2022

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