Role of Tumor and Stroma-Derived IGF/IGFBPs in Pancreatic Cancer

Role of Tumor and Stroma-Derived IGF/IGFBPs in Pancreatic Cancer

Pancreatic cancer (PC) is the utmost stroma-rich cancer, which is accompanied by fibrotic reactions that stimulate interactions between tumor cells and stroma to promote tumor progression. Considerable research evidence denotes that insulin-like growth factor (IGF)/IGF binding proteins (IGFBP) signa...

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Bibliographic Details
Main Authors: Divya Thomas, Prakash Radhakrishnan
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
insulin-like growth factor signaling
insulin-like growth factor binding proteins
pancreatic cancer
extracellular matrix
tumor microenvironment
Online Access:https://www.mdpi.com/2072-6694/12/5/1228

Internet

https://www.mdpi.com/2072-6694/12/5/1228

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