A novel dual luciferase based high throughput assay to monitor autophagy in real time in yeast S. cerevisiae

Background: Macroautophagy is a cellular response to starvation wherein superfluous and damaged cytoplasmic constituents are degraded to provide energy for survival and to maintain cellular homeostasis. Dysfunctional autophagy is attributed to disease progression in several pathological conditions a...

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Bibliographic Details
Main Authors: Piyush Mishra, Shashank Rai, Ravi Manjithaya
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240558081630293X