Dynamic Modelling of Phosphorolytic Cleavage Catalyzed by Pyrimidine-Nucleoside Phosphorylase

Dynamic Modelling of Phosphorolytic Cleavage Catalyzed by Pyrimidine-Nucleoside Phosphorylase

Pyrimidine-nucleoside phosphorylases (Py-NPases) have a significant potential to contribute to the economic and ecological production of modified nucleosides. These can be produced via pentose-1-phosphates, an interesting but mostly labile and expensive precursor. Thus far, no dynamic model exists f...

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Bibliographic Details
Main Authors: Robert T. Giessmann, Niels Krausch, Felix Kaspar, Mariano Nicolas Cruz Bournazou, Anke Wagner, Peter Neubauer, Matthias Gimpel
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Processes
Subjects:
enzymatic reaction
reversible reaction
dynamic modelling
pyrimidine-nucleoside phosphorylase
spectroscopic assay
process kinetics
ODE model
Online Access:https://www.mdpi.com/2227-9717/7/6/380

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https://www.mdpi.com/2227-9717/7/6/380

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