Pirfenidone nanoparticles improve corneal wound healing and prevent scarring following alkali burn.

To evaluate the effects of pirfenidone nanoparticles on corneal re-epithelialization and scarring, major clinical challenges after alkali burn.Effect of pirfenidone on collagen I and α-smooth muscle actin (α-SMA) synthesis by TGFβ induced primary corneal fibroblast cells was evaluated by immunoblott...

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Bibliographic Details
Main Authors: Sushovan Chowdhury, Rajdeep Guha, Ruchit Trivedi, Uday B Kompella, Aditya Konar, Sarbani Hazra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3734236?pdf=render