An upstream open reading frame regulates LST1 expression during monocyte differentiation.

The regulation of gene expression depends on the interplay of multiple factors at the transcriptional and translational level. Upstream open reading frames (uORFs) play an important role as translational repressors of main ORFs and their presence or usage in transcripts can be regulated by different...

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Bibliographic Details
Main Authors: Christian Schiller, Carina Nowak, Kalliope N Diakopoulos, Ulrich H Weidle, Elisabeth H Weiss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4015914?pdf=render