Neuropathologically distinct prion strains give rise to similar temporal profiles of behavioral deficits
Mouse-adapted scrapie strains have been characterized by vacuolation profiles and incubation times, but the behavioral consequences have not been well studied. Here, we compared behavioral impairments produced by ME7, 79A, 22L, and 22A strains in C57BL/6J mice. We show that early impairments on burr...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2005-03-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996104002104 |