The Road of Solid Tumor Survival: From Drug-Induced Endoplasmic Reticulum Stress to Drug Resistance

The Road of Solid Tumor Survival: From Drug-Induced Endoplasmic Reticulum Stress to Drug Resistance

Endoplasmic reticulum stress (ERS), which refers to a series of adaptive responses to the disruption of endoplasmic reticulum (ER) homeostasis, occurs when cells are treated by drugs or undergo microenvironmental changes that cause the accumulation of unfolded/misfolded proteins. ERS is one of the k...

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Bibliographic Details
Main Authors: Shulong Cao, Jingyi Tang, Yichun Huang, Gaofeng Li, Zhuoya Li, Wenqi Cai, Yuning Yuan, Junlong Liu, Xuqun Huang, Haiyuan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
drug resistance
endoplasmic reticulum stress
solid tumor
unfolded protein response
immunosuppression
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.620514/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.620514/full

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