Relationship between -181 (A/G) region single nucleotide polymorphisms of matrilysin gene promoter and the onset and prevalence of colorectal cancer using tetra-primer ARMS PCR and RFLP-PCR techniques

Aim: MMP enzymes are a family of membrane proteins that are capable of digesting extracellular matrix compounds (ECM) and basement membrane. Matrilysin enzyme is the smallest member of MMP family that is encoded by MMP-7 gene (matrilysin). According to the reports, G allele of -181 A/G single nucle...

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Bibliographic Details
Main Authors: Majid Motovali-Bashi, Zahra Sadeghi, Simin Hemati
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2015-11-01
Series:Basic & Clinical Cancer Research
Subjects:
Online Access:https://bccr.tums.ac.ir/index.php/bccrj/article/view/174