Expression of FGD4 positively correlates with the aggressive phenotype of prostate cancer

Expression of FGD4 positively correlates with the aggressive phenotype of prostate cancer

Abstract Background FGD4 (Frabin) is an F-actin binding protein with GTP/GDP exchange activity specific for CDC42. It is involved in reorganization of the actin cytoskeleton, which requires both actin binding and CDC42 activating function of FGD4. Expression of FGD4 is altered in patients with heter...

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Bibliographic Details
Main Authors: Alexia Bossan, Richard Ottman, Thomas Andl, Md Faqrul Hasan, Nupam Mahajan, Domenico Coppola, Ratna Chakrabarti
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Cancer
Subjects:
Rho GEF
Prostate cancer
Cell cycle
Cell migration
Drug sensitivity
Online Access:http://link.springer.com/article/10.1186/s12885-018-5096-9

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http://link.springer.com/article/10.1186/s12885-018-5096-9

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