Effect of Process Conditions on Particle Size and Shape in Continuous Antisolvent Crystallisation of Lovastatin

Lovastatin crystals often exhibit an undesirable needle-like morphology. Several studies have shown how a needle-like morphology can be modified in antisolvent crystallisation with the use of additives, but there is much less experimental work demonstrating crystal shape modification without the use...

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Bibliographic Details
Main Authors: John McGinty, Magdalene W. S. Chong, Andrew Manson, Cameron J. Brown, Alison Nordon, Jan Sefcik
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/10/10/925