Electrostatic interaction of tumor-targeting adenoviruses with aminoclay acquires enhanced infectivity to tumor cells inside the bladder and has better cytotoxic activity

Electrostatic interaction of tumor-targeting adenoviruses with aminoclay acquires enhanced infectivity to tumor cells inside the bladder and has better cytotoxic activity

In a previous report, 3-aminopropyl functionalized magnesium phyllosilicate (aminoclay) improved adenovirus transduction efficiency by shielding the negative surface charges of adenovirus particles. The present study analyzed the physicochemical characterization of the electrostatic complex of adeno...

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Bibliographic Details
Main Authors: Soo-Yeon Kim, Whi-An Kwon, Seung-Pil Shin, Ho Kyung Seo, Soo-Jeong Lim, Yuh-Seog Jung, Hyo-Kyung Han, Kyung-Chae Jeong, Sang-Jin Lee
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Drug Delivery
Subjects:
aminoclay
bladder cancer
gene therapy
adenovirus
transduction
Online Access:http://dx.doi.org/10.1080/10717544.2017.1413450

Internet

http://dx.doi.org/10.1080/10717544.2017.1413450

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