Effect of Metformin on the Medullary Thyroid Cancer Cells

Background. Medullary thyroid cancer (MTC) is associated with activation of mTOR signaling pathways. Recent studies showed that the anti-diabetic agent metformin decreases proliferation of cancer cells through AMPK-dependent inhibition of mTOR. The objective of current study — assessment of the effe...

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Bibliographic Details
Main Authors: V.G. KHOPERIA, V.V. VASKO
Format: Article
Language:English
Published: Publishing House Zaslavsky 2013-08-01
Series:Mìžnarodnij Endokrinologìčnij Žurnal
Subjects:
Online Access:http://iej.zaslavsky.com.ua/article/view/84481