Maresin 1, a Proresolving Lipid Mediator, Ameliorates Liver Ischemia-Reperfusion Injury and Stimulates Hepatocyte Proliferation in Sprague-Dawley Rats

Maresin 1, a Proresolving Lipid Mediator, Ameliorates Liver Ischemia-Reperfusion Injury and Stimulates Hepatocyte Proliferation in Sprague-Dawley Rats

Maresin-1 (MaR1) is a specialized pro-resolving mediator, derived from omega-3 fatty acids, whose functions are to decrease the pro-inflammatory and oxidative mediators, and also to stimulate cell division. We investigated the hepatoprotective actions of MaR1 in a rat model of liver ischemia-reperfu...

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Bibliographic Details
Main Authors: Gonzalo Soto, María José Rodríguez, Roberto Fuentealba, Adriana V. Treuer, Iván Castillo, Daniel R. González, Jessica Zúñiga-Hernández
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
liver preconditioning
bioactive lipids
mitotic activity index
cytokines
transcription factors
Online Access:https://www.mdpi.com/1422-0067/21/2/540

Internet

https://www.mdpi.com/1422-0067/21/2/540

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