Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease?

Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease?

Abstract Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative disorders that share genetic risk factors and pathological hallmarks. Intriguingly, these shared factors result in a high rate of comorbidity of these diseases in patients. Intracellular protein aggr...

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Bibliographic Details
Main Authors: Zhiqiang Deng, Patricia Sheehan, Shi Chen, Zhenyu Yue
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Molecular Neurodegeneration
Subjects:
Amyotrophic lateral sclerosis
Frontotemporal dementia
Autophagy
Disease-associated genes
Autophagy-related genes
Online Access:http://link.springer.com/article/10.1186/s13024-017-0232-6

Internet

http://link.springer.com/article/10.1186/s13024-017-0232-6

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