OSBP-related protein 8 (ORP8) regulates plasma and liver tissue lipid levels and interacts with the nucleoporin Nup62.

OSBP-related protein 8 (ORP8) regulates plasma and liver tissue lipid levels and interacts with the nucleoporin Nup62.

We earlier identified OSBP-related protein 8 (ORP8) as an endoplasmic reticulum oxysterol-binding protein implicated in cellular lipid homeostasis. We now investigated its action in hepatic cells in vivo and in vitro. Adenoviral overexpression of ORP8 in mouse liver induced a decrease of cholesterol...

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Bibliographic Details
Main Authors: Tianhong Zhou, Shiqian Li, Wenbin Zhong, Terhi Vihervaara, Olivier Béaslas, Julia Perttilä, Wei Luo, Yingliang Jiang, Markku Lehto, Vesa M Olkkonen, Daoguang Yan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3115989?pdf=render

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http://europepmc.org/articles/PMC3115989?pdf=render

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