Astrocytes Regulate the Development and Maturation of Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells

Summary: Retinal ganglion cells (RGCs) form the connection between the eye and the brain, with this connectivity disrupted in numerous blinding disorders. Previous studies have demonstrated the ability to derive RGCs from human pluripotent stem cells (hPSCs); however, these cells exhibited some char...

Full description

Bibliographic Details
Main Authors: Kirstin B. VanderWall, Ridhima Vij, Sarah K. Ohlemacher, Akshayalakshmi Sridhar, Clarisse M. Fligor, Elyse M. Feder, Michael C. Edler, Anthony J. Baucum, II, Theodore R. Cummins, Jason S. Meyer
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118305290