An In Vitro Barrier Model of the Human Submandibular Salivary Gland Epithelium Based on a Single Cell Clone of Cell Line HTB-41: Establishment and Application for Biomarker Transport Studies

The blood–saliva barrier (BSB) consists of the sum of the epithelial cell layers of the oral mucosa and salivary glands. In vitro models of the BSB are inevitable to investigate and understand the transport of salivary biomarkers from blood to saliva. Up to now, standardized, cell line-based models...

Full description

Bibliographic Details
Main Authors: Grace C. Lin, Merima Smajlhodzic, Anna-Maria Bandian, Heinz-Peter Friedl, Tamara Leitgeb, Sabrina Oerter, Kerstin Stadler, Ulrich Giese, Johannes R. Peham, Lynne Bingle, Winfried Neuhaus
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/8/9/302