Combining Neurotrophin-Transduced Schwann Cells and Rolipram to Promote Functional Recovery from Subacute Spinal Cord Injury

Combining Neurotrophin-Transduced Schwann Cells and Rolipram to Promote Functional Recovery from Subacute Spinal Cord Injury

Following spinal cord injury (SCI), both an inhibitory environment and lack of intrinsic growth capacity impede axonal regeneration. In a previous study, prevention of cyclic adenosine monophosphate (AMP) hydrolysis by the phosphodiesterase-4 inhibitor rolipram, in combination with Schwann cell (SC)...

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Bibliographic Details
Main Authors: Govinder Flora, Gravil Joseph, Samik Patel, Amanpreet Singh, Drew Bleicher, David J. Barakat, Jack Louro, Stephanie Fenton, Maneesh Garg, Mary Bartlett Bunge, Damien D. Pearse Ph.D
Format: Article
Language:English
Published: SAGE Publishing 2013-12-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X658872

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https://doi.org/10.3727/096368912X658872

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