A novel xenograft model in zebrafish for high-resolution investigating dynamics of neovascularization in tumors.

Tumor neovascularization is a highly complex process including multiple steps. Understanding this process, especially the initial stage, has been limited by the difficulties of real-time visualizing the neovascularization embedded in tumor tissues in living animal models. In the present study, we ha...

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Bibliographic Details
Main Authors: Chengjian Zhao, Xiaofei Wang, Yuwei Zhao, Zhimian Li, Shuo Lin, Yuquan Wei, Hanshuo Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3135597?pdf=render